JOURNAL OF SCIENTIFIC PERSPECTIVES 2019-05-10T11:15:27+03:00 Ozlem YAYINTAS Open Journal Systems <p style="text-align: justify;"><em><strong>Journal of Scientific Perspectives</strong> (E-ISSN: 2587-3008 &amp; DOI Prefix:&nbsp;10.26900)&nbsp;is a&nbsp;scholarly&nbsp;and&nbsp;international peer-reviewed journal&nbsp;which started to be published in&nbsp; 2017. It is an&nbsp;open-access electronic journal&nbsp;which is published quarterly in&nbsp;January, April, July, and&nbsp;October</em><strong><em>.</em></strong><em>&nbsp;It is aimed at promoting research worldwide&nbsp;and publishes basic and advanced research work from the fields of&nbsp;basic science and engineering, natural science</em><strong><em>s</em></strong><em>&nbsp;and&nbsp;health sciences. Thus, it provides a forum for researchers for scholarly exchange of ideas, knowledge, and experiences on current issues. The original research papers, technical notes, letter to the editor, debates, case presentations, and reviews, only in&nbsp;English,&nbsp;are published in the journal. All articles published in the journal, are assigned the&nbsp;DOI number. Article submission and follow-up process are carried out by the manuscript submission system.</em></p> THE EFFECT OF COMBINATION OF BORIC ACID AND LITHIUM CARBONATE ON SINTERING AND MICROSTRUCTURE IN SINGLE FIRING WALL TILE 2019-05-10T11:15:27+03:00 Savaş ELMAS İsmail TARHAN <p><em>The aim of this study was to determine the effect of boric acid and lithium carbonate on microstructure and sintering characteristics of wall tile after firing. Amount of Li2 (CO3) (0.1-0.3-0.6- 0.9-1.2-4 wt.%) were added in wall tile corresponding to each constant amount of added of H3BO3 (0.1-0.3-0.6-0.9-1.2-2 wt.%). All samples were fired in 1135 0C 35 minutes in an industrial fast firing kiln. Dry strength, fired strength, water absorption and colorimeter values of all samples were determined after firing. Scanning electron microscope (SEM), x-ray diffraction (XRD) analysis, optical dilatometer measurements were performed in order to determine the microstructure and melting temperature for prescribed purpose (1-2-7-8-11-32-37). Standard (1) and alternative (8) receipe’s thermogravimetric and diferantial thermal analyses were performed. 37 (2% H3BO3 + 4% Li2 (CO3) recipe’s sintering starting temperature was 984 0C. In the recipe 8 (0.3% H3BO3 + 0.1% Li2(CO3) is an alternative to the standard wall tile, which can be used with higher strength values. </em></p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement## pH-RESPONSIVE CARBOXYMETHYL CELLULOSE CONJUGATED SUPERPARAMAGNETIC IRON OXIDE NANOCARRIERS 2019-05-10T11:15:27+03:00 Seda DEMİREL TOPEL Tulin GÜRKAN POLAT <p><em>In the present study, polyethyleneimine (PEI) coated superparamagnetic iron oxide nanoparticles (SPIONs) having the size of 15 nm in diameter with high magnetic saturation (60 emu/g) have been prepared by co-precipitation method. The synthesized PEI-Fe<sub>3</sub>O<sub>4</sub> nanoparticles have been fully characterized by transmission electron microscope (TEM), dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD) techniques. The free amine groups on the PEI-Fe<sub>3</sub>O<sub>4 </sub>surface has been covalently functionalized with carboxymethyl cellulose (CMC) by the catalysis of N,N'-Dicyclohexylcarbodiimide (DCC) and N, N'-Dimethylpyridin-4-amine (DMAP) coupling to produce CMC-Fe<sub>3</sub>O<sub>4</sub> nanocarriers. The prepared CMC-Fe<sub>3</sub>O<sub>4</sub> nanocarriers have been loaded with a well-known anti-tumor drug doxorubicin (Dox) and investigated its loading and releasing profiles from the nanocarrier. The CMC acted as an excellent nanocarrier for Dox with a loading efficiency ≈ 86%. The drug releasing profile has been studied at different pH values (3.5; 5.5; and 7.4). When the pH of the release medium (phosphate buffer solution) was changed from 7.4 to 5.5 or 3.6, the drug release has been increased which indicates that the drug releasing is pH dependent.</em></p> <p><em>&nbsp;</em></p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement## DETERMINATION OF SOME MACRO ELEMENT CONCENTRATIONS AND CHLOROPHYLL-A DISTRIBUTION IN A SHALLOW LAKE WETLAND (GÖKÇEADA SALT LAKE LAGOON, ÇANAKKALE/TURKEY) 2019-05-10T11:15:26+03:00 Herdem ASLAN Onur GÖNÜLAL <p><em>In this study, the macro element concentrations and chlorophyll-a distribution in the Gökçeada Salt Lake Lagoon which is in the category of Shallow Lake Wetland in Gökçeada (Canakkale) were evaluated. For this purpose, some macro elements (Nitrite, Nitrate, Sulfate, Phosphate, Calcium, Magnesium, Potassium, and Phosphorus) and chlorophyll-a levels as well as water temperature and dissolved oxygen values were measured in 2016 as seasonally (January, May, August, November) from three stations. During the autumn season, nitrite, nitrate, phosphate and sulfate values measured as 5.65 ppm; 16.9 ppm; 77 ppm; and 8547 ppm, respectively. As a result, the macro element concentrations deposited in the sediment and the chlorophyll-a amounts of the lake was signed to the ecological conditions are very suitable for the development of eutrophication. In the end of the study, some suggestions were done to protect the ecosystem balance.</em></p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement## RSM METHOD AND OPTIMIZATION OF HARD COATED SOFT SUGAR PROCESS PARAMETERS 2019-05-10T11:15:27+03:00 Özge EYYÜPOĞLU Mehmet Ali MARANGOZ Bora YEŞİLTEPE <p><em>Nowadays, the textural characteristics of foods affect the consumers' enjoyment about them. Providing ideal textural properties, especially in multi stage food production processes, is a complex and sensitive work that must be carried out with high precision. Hard sugar coated chewy product, “Chewy Drage” is highly preferred by the confectionery consumers all over the world. In this work, the changes in the physical behaviors of “Chewy Drage” with the changes in textural and process parameters was studied. Each process parameter was separately optimized and the relationship between those physical properties was elaborated.</em></p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement## USING FIRED WALL TILE’S SCRAPS IN FLOOR TILE BODY 2019-05-10T11:15:26+03:00 Savaş ELMAS <p><em>The effect of the addition of the fired wall tile’s scraps in floor tile body was studied. The fired wall tile’s scraps were added to floor tile body according to 1.96-5.66-10.71-17.85 wt. % ratios. The sintering behavior of the floor tile was evaluated by measuring the water absorption, fired shrinkage, dry shrinkage and fired strength. In addition, microstructure and phase analysis were investigated by scanning electron microscopy (SEM), energy dispersive x-ray (EDX) and x-ray analysis (XRD). Samples were fired in industrial type kiln which was continuous production at 1189 <sup>0</sup>C in 40 minutes. It was determined that the addition of 5.66 wt. % of the wall tile’s scrap to the floor tile had an effect of increasing the fired strength value. In the XRD analysis, anorthite phase was observed which shows fired strength and chemical resistance.</em></p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement## HADAMARD, SIMPSON AND OSTROWSKI TYPE INEQUALITIES FOR E-CONVEXITY 2019-05-10T11:15:26+03:00 Musa ÇAKMAK <p>In this study, we proposed a new definition to give a different perspective to convex functions. We have introduced the expansion of Hadamard, midpoint Hadamard, trapezoid Hadamard, Simpson and Ostrowski inequalities for the newly defined classes of convex functions.</p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement## THE IMPORTANCE OF THE MEDICINAL PLANT NASTURTIUM OFFICINALE L. IN THE ANTICANCER ACTIVITY RESEARCH 2019-05-10T11:15:26+03:00 Erkan YALÇINKAYA Serdar ÖZGÜÇ Yusuf Orçun TÖRER Ulvi ZEYBEK <p><em>Cancer is known as one of the main cause of deathworldwide. It is difficult to discover nove lagents that selectively kill tumor cels or inhibit their proliferation without general toxicity.&nbsp; Searching for more active, more selective and less toxic compounds are the main targets of cancer researchs. Nasturtium&nbsp; officinale L. has been used for a long time as a food and&nbsp; medicinal plant widely distrubuted areas of world for ages.Main therapeutic effect of plant is because of rich&nbsp; </em><em>essential nutrients as well as non-essential health-promoting phytochemicals phenolics and glucosinolates.</em><em> The plant&nbsp; has antiviral, antiinflammatory,diuretic, expectorant, anti-diabetic, hepatoprotective, antihyperlipidemic and anticancer&nbsp; properties. The aim of this study is to review the Nasturtium officinale L. compounds and search for their effects against various cancer cell lines.</em></p> 2019-04-30T00:00:00+03:00 ##submission.copyrightStatement##