JOURNAL OF SCIENTIFIC PERSPECTIVES <p style="text-align: justify;"><em><strong>Journal of Scientific Perspectives</strong> (E-ISSN: 2587-3008 &amp; DOI Prefix:&nbsp;10.26900)&nbsp;is a&nbsp;scholarly&nbsp;and&nbsp;international peer-reviewed journal&nbsp;which started to be published in&nbsp; 2017. It is an&nbsp;open-access electronic journal&nbsp;which is published quarterly in&nbsp;January, April, July, and&nbsp;October</em><strong><em>.</em></strong><em>&nbsp;It is aimed at promoting research worldwide&nbsp;and publishes basic and advanced research work from the fields of&nbsp;basic science and engineering, natural science</em><strong><em>s</em></strong><em>&nbsp;and&nbsp;health sciences. Thus, it provides a forum for researchers for scholarly exchange of ideas, knowledge, and experiences on current issues. The original research papers, technical notes, letter to the editor, debates, case presentations, and reviews, only in&nbsp;English,&nbsp;are published in the journal. All articles published in the journal, are assigned the&nbsp;DOI number. Article submission and follow-up process are carried out by the manuscript submission system.</em></p> RATING ACADEMY Ar-Ge Yazılım Yayıncılık Eğitim Danışmanlık ve Organizasyon Ticaret Ltd. Şti. en-US JOURNAL OF SCIENTIFIC PERSPECTIVES 0000-0000 <p><em>When the&nbsp; article is accepted for publication in the </em><em>Journal of Scientific Perspectives</em><em>&nbsp;authors transfer all copyright in the article to the </em><em>Rating Academy </em><em>Ar-Ge Yazılım Yayıncılık Eğitim Danışmanlık ve Organizasyon Ticaret Ltd. Şti</em><em>.</em><em>The authors reserve all proprietary right other than copyright, such as patent rights.&nbsp;</em></p> <p><em>Everyone who is listed as an author in this article should have made a substantial, direct, intellectual contribution to the work and</em><em> should take public responsibility for it.</em></p> <p><em>Th</em><em>is paper contains works that have </em><em>not previously published or not under consideration for publication in other journals. </em></p> THE EFFECT OF COMBINATION OF BORIC ACID AND LITHIUM CARBONATE ON SINTERING AND MICROSTRUCTURE IN SINGLE FIRING WALL TILE <p><em>The aim of this study was to determine the effect of boric acid and lithium carbonate on microstructure and sintering characteristics of wall tile after firing. Amount of Li2 (CO3) (0.1-0.3-0.6- 0.9-1.2-4 wt.%) were added in wall tile corresponding to each constant amount of added of H3BO3 (0.1-0.3-0.6-0.9-1.2-2 wt.%). All samples were fired in 1135 0C 35 minutes in an industrial fast firing kiln. Dry strength, fired strength, water absorption and colorimeter values of all samples were determined after firing. Scanning electron microscope (SEM), x-ray diffraction (XRD) analysis, optical dilatometer measurements were performed in order to determine the microstructure and melting temperature for prescribed purpose (1-2-7-8-11-32-37). Standard (1) and alternative (8) receipe’s thermogravimetric and diferantial thermal analyses were performed. 37 (2% H3BO3 + 4% Li2 (CO3) recipe’s sintering starting temperature was 984 0C. In the recipe 8 (0.3% H3BO3 + 0.1% Li2(CO3) is an alternative to the standard wall tile, which can be used with higher strength values. </em></p> Savaş ELMAS İsmail TARHAN ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 85 98 10.26900/jsp.3.010 pH-RESPONSIVE CARBOXYMETHYL CELLULOSE CONJUGATED SUPERPARAMAGNETIC IRON OXIDE NANOCARRIERS <p><em>In the present study, polyethyleneimine (PEI) coated superparamagnetic iron oxide nanoparticles (SPIONs) having the size of 15 nm in diameter with high magnetic saturation (60 emu/g) have been prepared by co-precipitation method. The synthesized PEI-Fe<sub>3</sub>O<sub>4</sub> nanoparticles have been fully characterized by transmission electron microscope (TEM), dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD) techniques. The free amine groups on the PEI-Fe<sub>3</sub>O<sub>4 </sub>surface has been covalently functionalized with carboxymethyl cellulose (CMC) by the catalysis of N,N'-Dicyclohexylcarbodiimide (DCC) and N, N'-Dimethylpyridin-4-amine (DMAP) coupling to produce CMC-Fe<sub>3</sub>O<sub>4</sub> nanocarriers. The prepared CMC-Fe<sub>3</sub>O<sub>4</sub> nanocarriers have been loaded with a well-known anti-tumor drug doxorubicin (Dox) and investigated its loading and releasing profiles from the nanocarrier. The CMC acted as an excellent nanocarrier for Dox with a loading efficiency ≈ 86%. The drug releasing profile has been studied at different pH values (3.5; 5.5; and 7.4). When the pH of the release medium (phosphate buffer solution) was changed from 7.4 to 5.5 or 3.6, the drug release has been increased which indicates that the drug releasing is pH dependent.</em></p> <p><em>&nbsp;</em></p> Seda DEMİREL TOPEL Tulin GÜRKAN POLAT ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 99 110 10.26900/jsp.3.011 DETERMINATION OF SOME MACRO ELEMENT CONCENTRATIONS AND CHLOROPHYLL-A DISTRIBUTION IN A SHALLOW LAKE WETLAND (GÖKÇEADA SALT LAKE LAGOON, ÇANAKKALE/TURKEY) <p><em>In this study, the macro element concentrations and chlorophyll-a distribution in the Gökçeada Salt Lake Lagoon which is in the category of Shallow Lake Wetland in Gökçeada (Canakkale) were evaluated. For this purpose, some macro elements (Nitrite, Nitrate, Sulfate, Phosphate, Calcium, Magnesium, Potassium, and Phosphorus) and chlorophyll-a levels as well as water temperature and dissolved oxygen values were measured in 2016 as seasonally (January, May, August, November) from three stations. During the autumn season, nitrite, nitrate, phosphate and sulfate values measured as 5.65 ppm; 16.9 ppm; 77 ppm; and 8547 ppm, respectively. As a result, the macro element concentrations deposited in the sediment and the chlorophyll-a amounts of the lake was signed to the ecological conditions are very suitable for the development of eutrophication. In the end of the study, some suggestions were done to protect the ecosystem balance.</em></p> Herdem ASLAN Onur GÖNÜLAL ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 111 118 10.26900/jsp.3.012 RSM METHOD AND OPTIMIZATION OF HARD COATED SOFT SUGAR PROCESS PARAMETERS <p><em>Nowadays, the textural characteristics of foods affect the consumers' enjoyment about them. Providing ideal textural properties, especially in multi stage food production processes, is a complex and sensitive work that must be carried out with high precision. Hard sugar coated chewy product, “Chewy Drage” is highly preferred by the confectionery consumers all over the world. In this work, the changes in the physical behaviors of “Chewy Drage” with the changes in textural and process parameters was studied. Each process parameter was separately optimized and the relationship between those physical properties was elaborated.</em></p> Özge EYYÜPOĞLU Mehmet Ali MARANGOZ Bora YEŞİLTEPE ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 119 132 10.26900/jsp.3.013 USING FIRED WALL TILE’S SCRAPS IN FLOOR TILE BODY <p><em>The effect of the addition of the fired wall tile’s scraps in floor tile body was studied. The fired wall tile’s scraps were added to floor tile body according to 1.96-5.66-10.71-17.85 wt. % ratios. The sintering behavior of the floor tile was evaluated by measuring the water absorption, fired shrinkage, dry shrinkage and fired strength. In addition, microstructure and phase analysis were investigated by scanning electron microscopy (SEM), energy dispersive x-ray (EDX) and x-ray analysis (XRD). Samples were fired in industrial type kiln which was continuous production at 1189 <sup>0</sup>C in 40 minutes. It was determined that the addition of 5.66 wt. % of the wall tile’s scrap to the floor tile had an effect of increasing the fired strength value. In the XRD analysis, anorthite phase was observed which shows fired strength and chemical resistance.</em></p> Savaş ELMAS ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 133 140 10.26900/jsp.3.014 HADAMARD, SIMPSON AND OSTROWSKI TYPE INEQUALITIES FOR E-CONVEXITY <p>In this study, we proposed a new definition to give a different perspective to convex functions. We have introduced the expansion of Hadamard, midpoint Hadamard, trapezoid Hadamard, Simpson and Ostrowski inequalities for the newly defined classes of convex functions.</p> Musa ÇAKMAK ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 141 158 10.26900/jsp.3.015 THE IMPORTANCE OF THE MEDICINAL PLANT NASTURTIUM OFFICINALE L. IN THE ANTICANCER ACTIVITY RESEARCH <p><em>Cancer is known as one of the main cause of deathworldwide. It is difficult to discover nove lagents that selectively kill tumor cels or inhibit their proliferation without general toxicity.&nbsp; Searching for more active, more selective and less toxic compounds are the main targets of cancer researchs. Nasturtium&nbsp; officinale L. has been used for a long time as a food and&nbsp; medicinal plant widely distrubuted areas of world for ages.Main therapeutic effect of plant is because of rich&nbsp; </em><em>essential nutrients as well as non-essential health-promoting phytochemicals phenolics and glucosinolates.</em><em> The plant&nbsp; has antiviral, antiinflammatory,diuretic, expectorant, anti-diabetic, hepatoprotective, antihyperlipidemic and anticancer&nbsp; properties. The aim of this study is to review the Nasturtium officinale L. compounds and search for their effects against various cancer cell lines.</em></p> Erkan YALÇINKAYA Serdar ÖZGÜÇ Yusuf Orçun TÖRER Ulvi ZEYBEK ##submission.copyrightStatement## 2019-04-30 2019-04-30 3 2 159 164 10.26900/jsp.3.016